Probe on virus

In what way lungs cells differ from other organs, which makes as a target for the virus.
Our organs of other cells are immune within the body and respiratory alone
gets affected by apoptosis of the cells?

Can the asthma inhalers helps,

what is the effect of increasing the temperature of air /

inhalation https://pubmed.ncbi.nlm.nih.gov/8151855/

UV rays may be helpful not as a vaccine, but to minimize spread.
by varying wavelength
Uv & Corona

Is the spread accelerates in night, compared to day can't a UV based system

be introduced to control things?

https://www.sciencedaily.com/releases/2007/10/071030080626.htm

Does this virus affect a pregnant woman?
The kids under 5 are often take vaccinations, is any infant infected?
Does any of this vaccine help?
https://www.immunize.org/catg.d/p4019.pdf
https://academic.oup.com/jid/article/195/7/965/803871

Is the cold climate a reason or is it humidity that spreads the disease?

Is it hydrophobic? Did it affect any marine life/people at seashore city?

The virus itself an evolved mutated one can the host infected with a bacterial
or another virus mutation make it inert? host mapping?

Unlike elders, kids remain indoors and the rodents avoid the lights.

Does this multiply in the presence or absence of sunlight/UV rays?
probability of spread in day or night?

Can the spike-based virus following a similar viral glycoprotein
vaccination be tried out? Say the vaccines of HIV can be used?

https://en.wikipedia.org/wiki/CD4 (CD4 attack mechanism by HIV)

https://www.webmd.com/hiv-aids/guide/nutrition-hiv-aids-enhancing-quality-life#1

https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(13)62269-2/fulltext

Can the H5N1 virus vaccine be used, as there is a similarity in the symptoms:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4034094/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5751439/

Study of ACE2 SARS and CORONA Similarity:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1287568/

The Viral Glycoprotein in the spikes gets passed through the membrane,
but what activates/ releases the RNA who intimates
the virus that it's inside the cell?

The action of releasing the RNA and hacking the cell is
instantaneous or it takes time?

The Kids and Rats are quite active, some research shows
glycoprotein are high in diabetic patients and rats and kids with
diabetic still immune to the virus. Are the lab rats/newborn rats immune to the virus?

Does the virus get passed through the patients to the soil after
cremations and microbes and remains in an inert state?

Can the immune system of a different organ be compared with that
of the human and design a vaccine?
Cytokine Storm https://covid.yale.edu/ysm/news-article/23809/

Immune modulator

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4684115/

Immune Modulator

Autism and CD4 immunity:
https://jneuroinflammation.biomedcentral.com/articles/10.1186/1742-2094-9-158

Can the air be extracted once the disease is found? and use the sample to
develop an antigen/vaccine?

Lung-failure

Given that Ape is the nearest to human, why the virus is not at best to it and rendered in active ?

Ape-Genetics

21. CD4 research

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118265/

https://www.frontiersin.org/articles/10.3389/fimmu.2017.00197/full

Nanotechnology in Vaccine design:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180194/

Few Questions:

It's known fact bats are a carrier of infections but still immune to them, can a study of how immunity of bats differs from humans help to discover a drug? Probably the behaviour pattern night dwellers and food chain would have changed in the evolution of life forms and this helped the bats to get adopted to the virus study on food consumption of immune bats can it help? Does the infection from various virus nullify the effect of COVID in bats and similar species?

Are there any other species we are aware of that are infected and have proved to be fatal? for e.g. chimpanzee and monkeys?

Is there any difference in oxytocin levels in Bats and humans, can this lead to immunity difference? In bats are female/new-borns are immune or all are immune?

Africa is sparse, though the infection rate is high, is their food habit and the environmental condition has a role to play?

Some turtles live long, does the study of their DNA help in medicine to increase the life span of humans, ref: https://www.businessinsider.in/science/11-of-the-oldest-animals-ever-ranked-by-age/articleshow/69010149.cms

Do Archeology and Climate change have a role to play? many advanced civilizations became extinct due to deadly disease has such diseases got unleashed again while studying history, the virus needs a host it can be seen as an untriggered bomb without a host, has it became alive while coming in contact with air?

Ref:

https://www.facebook.com/IndSciCovid/

https://fold.it/

https://www.youtube.com/watch?v=0DJ91ZWXJiw

https://www.youtube.com/watch?v=3Uugj-zxA5E

understand vaccination https://www.youtube.com/watch?v=Atrx1P2EkiQ

https://www.youtube.com/watch?v=Atrx1P2EkiQ

https://askabiologist.asu.edu/epithelial-cells

Homemade mask:

https://www.youtube.com/watch?v=Atrx1P2EkiQ

https://www.who.int/emergencies/diseases/novel-coronavirus-2019/advice-for-public/when-and-how-to-use-masks

Ranking in protection

https://www.thomasnet.com/articles/other/how-surgical-masks-are-made/

Study on P2 vs Surgical Mask:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2662657/

Questions on Brain

Questions on Brain 1) By any chance brain of introverts differs from extrovert I feel so did you happen to explore it? 2) The story of Abhimanyu from what age the brain gets developed and understand do really kids hear and observe from the womb? 3) There are studies that say constantly skull sizes are changing so I believe the brain as well does so do you see in the human brain other forms of cortex will evolve? 4) How do stem cells form neurons or they get developed to certain parts of organs who make this decision this isn't the brain then even the cells have somewhat like a brain? 5) Do the size of male and female brains differs, some research says women's brains are often very good in communications how far is it true, in that case, all women need to be an extrovert which is not true! 6) At the end of the day, it is chemicals and electrical signals in the brain we can think brains as an apparatus that can create with its own composition of chemicals, over a

KateMarch 30, 2020 at 5:59 AM
There's a significant concept that should be explained: how viruses infect cells. The spike proteins on the envelope surface of all viruses act like a key to a host cellular receptor, in this case ACE2. Not all human cells or organs have ACE2 receptor!! So only cells with this receptor (like those in the airway) can be infected. All other cells are immune because the virus essentially can't see them, which is why covid19 mostly affects the airway. The ACE2 "key" that covid19 uses to enter a cell is very specific to covid19, and it's also how our body recognizes viruses to kill them. This is what makes viruses so tricky; they all have different keys, even different strains of the same virus (e.g. flu), so immunity to one virus doesn't translate well to another -- the same goes for vaccines. Immunity/vaccines are sort of like getting a copy of the key made, which is helpful to recognize that one key, but not others. Even other coronaviruses wouldn't be similar enough, although we don't have effective vaccines for the others anyway.

To be a bit more comprehensive, in order to get a copy of the key our body first responds to viral RNA after a cell is infected, but at that point it's too late to save the cell. So we rely on adaptive immunity (antibodies) from learning to recognize the key before the virus can even use it to infect a cell. Vaccines give us a sample key to safely learn without active infection, but e.g. an HIV vaccine can't give the key to covid19.

Calcium is a great target for host cellular processes -- it's involved in muscle contraction like you mentioned, for example. Calcium makes cells release their vesicles and secrete whatever it is they secrete (e.g. insulin), but aside from boosting cellular signaling in general, calcium/oxytocin wouldn't effect a virus.

Viruses need a host to survive and multiply. That's why they don't survive long on surfaces (moisture protects them from some damage which is why they can survive for a time), and I'd expect natural bodies of water would be too harsh an environment for the virus to survive despite all that moisture -- varying pH and different chemicals will break down the envelope before the RNA can get into a host and multiply. Same goes for soil; if there is no available host then the virus will die, and that key it uses is so specific it can only recognize the human ACE2 receptor. This is why viruses usually only affect one species, why you can't give covid19 to your pet cat. Once a patient is dead, the virus will run out of live cells to infect and live in, and it too will die by the time the body is in the ground.

I don't think I answered everything, but I hope this helps give a clearer picture of how viruses work!
UnknownMarch 30, 2020 at 3:10 PM
thank you

Thoughts on Research Subject by Non Research Student

Search This Blog

Probe on virus

Comments

Post a Comment

Popular posts from this blog

Probing of Cancer

Questions on Brain